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Besides Crohn's and ulcerative colitis, the IL-12- and IL-23-targeting drug is also approved for plaque. Stelara Commercial Song. the purple ad thing can be found in the video where the stelara website says in a heading "what is stelara and how does it work" over here, seems like this ad is maybe a different version of the original without the talking this is likely also important including the text displayed during the ad I feel really uncomfortable with these ads being allowed here. SOTYKTU (deucravacitinib) is a prescription medicine used to treat adults with moderate-to-severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy). 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